Hotels in Northeast Missouri

your current months are January, 2025 and February, 2025.
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February 2025

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Where to stay in Northeast Missouri?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Northeast Missouri

Top landmarks in Northeast Missouri

Learn more about Northeast Missouri

Northeast Missouri is hailed for its baseball and live music while top attractions include St. Louis Union Station. This family-friendly city has something for everyone including its theaters, restaurants, and sights like Mark Twain Birthplace State Historic Site and Mark Twain State Park.

St. Louis which includes interior views

Frequently asked questions

What accommodations do travelers recommend in Northeast Missouri?
The Green Tree Inn, River Sirens Hotel and Central Hotel are all properties that our guests really like.
Can I book a refundable accommodation in Northeast Missouri?
If you want the flexibility to change your travel plans to Northeast Missouri, most properties provide refundable* bookable rates. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Which Northeast Missouri hotels do our guests like for their central location?
Travelers like these properties for their convenient location: Live by Loews - St.Louis, Moonrise Hotel and OYO Hotel St. Louis Downtown City Center MO.
Where should I stay in Northeast Missouri if I want a cheap accommodation?
Pear Tree Inn St. Louis Airport, Quality Inn & Suites Hannibal and Sleep Inn & Suites O’Fallon MO - Technology Drive are a few accommodations you might want to consider that’ll save you money. You may want to browse more choices on our site, including 43 motels.
Where can I stay in Northeast Missouri if I want a vacation home instead of a traditional hotel?
If you want to find a good alternative to a hotel, review our selection of 829 vacation homes. In addition, there are 846 apartments and 159 condos.
Why should I book my Northeast Missouri hotel through Hotels.com?
There are plenty of reasons to book your Northeast Missouri travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.