Hotels in Upstate South Carolina

your current months are January, 2025 and February, 2025.
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Where to stay in Upstate South Carolina?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighbourhoods in Upstate South Carolina

Top landmarks in Upstate South Carolina

Learn more about Upstate South Carolina

Admired for its university life and sports, Upstate South Carolina features attractions such as Discovery Island Water Park and Frankie's Fun Park. This family-friendly city has something for everyone including its live music, restaurants and sights like Conestee Nature Preserve and Heritage Park.

Greenville - Spartanburg featuring mountains, views and a sunset
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Frequently asked questions

Can I book a refundable accommodation option in Upstate South Carolina?
If you want the flexibility to change your plans to Upstate South Carolina, most hotels offer refundable* rates that you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Upstate South Carolina if I want a holiday rental instead of a hotel?
If you’re looking for a good alternative to a hotel, review our selection of 1070 holiday homes. In addition, there are 113 apartments and 89 condos.
Why should I book my Upstate South Carolina hotel with Hotels.com?
There are lots of reasons to book your Upstate South Carolina trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.