Hotels in Murphysboro

your current months are January, 2025 and February, 2025.
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Where to stay in Murphysboro?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Murphysboro

Learn more about Murphysboro

Murphysboro is well known for its attractions such as Lake Murphysboro State Park and Shawnee National Forest.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Frequently asked questions

Can I book a refundable accommodation option in Murphysboro?
If you want the flexibility to change your plans to Murphysboro, most hotels offer refundable* rates that you can book. You can see this accommodation by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Murphysboro if I want a holiday rental instead of a hotel?
If you want to find a good alternative to a hotel, look over our selection of 16 holiday homes. You can also book one of the 6 cabins for your stay.
What will the weather in Murphysboro be like during my visit?
July and August are typically the warmest months in Murphysboro, when the average temperature is 24°C. January and February are the coldest months, when the average temperature is 4°C. April and March are the months with the most rain.
Why should I book my Murphysboro hotel with Hotels.com?
There are plenty of reasons to book your Murphysboro travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.