Hotels in Southern Illinois

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Check prices for these dates

Tonight
3 Jun - 4 Jun
Tomorrow
4 Jun - 5 Jun
This weekend
6 Jun - 8 Jun
Next weekend
13 Jun - 15 Jun

Where to stay in Southern Illinois?

Drury Plaza Hotel Mt. Vernon
Lobby

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1345)
The price is €96
includes taxes & fees
22 Jun - 23 Jun
Drury Plaza Hotel Mt. Vernon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:13 Jun - 15 Jun

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Front of property – evening/night

Makanda Inn

3.5 star property
Makanda
10/10Exceptional (32 reviews)
10% off
Price is €431
€215 per night
includes taxes & fees
Makanda Inn

Top neighbourhoods in Southern Illinois

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Eastport

The Eastport neighbourhood has lots to see, including Splash City Family Waterpark and Gateway Convention Center.

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Eastport

Top landmarks in Southern Illinois

Southern Illinois University

Southern Illinois University

If you'd like to get a taste of Carbondale student life, check out Southern Illinois University, located 1.1 mi (1.7 km) from central Carbondale.

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Southern Illinois University

Learn more about Southern Illinois

Southern Illinois is applauded for its entertainment and live music with such cultural attractions as Effingham Performance Center and Lincoln Log Cabin. Visitors highlight this family-friendly city's sports while sights include Salem Fairgrounds and Raccoon Lake Park.

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Southern Illinois which includes a sunset, forests and landscape views
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Frequently asked questions

Can I book a refundable accommodation option in Southern Illinois?
If you want the flexibility to change your plans to Southern Illinois, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Southern Illinois if I want a holiday rental instead of a hotel?
If you want a good alternative to a hotel, review our selection of 261 holiday homes. In addition, there are 77 apartments and 6 condos.
Why should I book my Southern Illinois hotel with Hotels.com?
There are plenty of reasons to book your Southern Illinois travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.