If you're looking to discover somewhere new, look no further than Santa Cruz. Whether you're planning to stay for a night or for the week, the area around Santa Cruz has accommodation options to fit every need. Search for hotels in Santa Cruz with Hotels.com by checking our online map. Our map displays the areas and neighbourhoods around all Santa Cruz hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santa Cruz hotel deals are here with our lowest price guarantee.
Hotels in Santa Cruz
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
9.0 out of 10, Wonderful, (191)
The price is €127
18 Jul - 19 Jul

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
9.2 out of 10, Wonderful, (244)
The price is €88
28 Jul - 29 Jul

Camino Real Hotel
Camino Real Hotel
8.8 out of 10, Excellent, (388)
The price is €119
1 Aug - 2 Aug

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
9.0 out of 10, Wonderful, (322)
The price is €112
7 Aug - 8 Aug

TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa Cruz
9.2 out of 10, Wonderful, (124)
The price is €93
14 Jul - 15 Jul

Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La Sierra
9.2 out of 10, Wonderful, (95)
The price is €90
3 Aug - 4 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:18 Jul - 20 Jul
Image gallery for HOTEL OSHO

HOTEL OSHO
Santa Cruz
9.0/10Wonderful (25 reviews)
10% off
Price is €125
€63 per night
Go beyond your typical stay in Santa Cruz
Top neighbourhoods in Santa Cruz
Hamacas
The Hamacas neighbourhood has lots to see, including Santa Cruz Zoo and Ventura Mall.
Top landmarks in Santa Cruz

Plaza 24 de Septiembre
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre – just one of the monuments in central Santa Cruz.
Learn more about Santa Cruz
Santa Cruz is applauded for its cultural attractions such as Cine Center and Guarani Nandereko Nomai Art and Culture Center.

Check out reviews of Santa Cruz hotels guests love

Camino Real Hotel
10/10 Excellent
Frequently asked questions
Find out more about Santa Cruz
Find out more about Santa Cruz
Keep exploring
Keep exploring
- Neighbourhoods
- Landmarks
- Star Rating
- Accommodation Types
- Facilities
- Hotels close to nearby airports
- Nearby cities
- Top Cities in Bolivia
- More Hotels
- Most popular destinations
- Hotels near Ventura Mall
- Hotels near Plaza 24 de Septiembre
- Hotels near Guembe Biocenter
- Hotels near Santa Cruz Zoo
- Hotels near San Lorenzo Cathedral
- Hotels near Ramon Tahuichi Aguilera Stadium
- Hotels near Cine Center
- Hotels near Blacutt Square
- Hotels near Lomas de Arena Regional Park
- Hotels near Las Brisas Shopping Center
- Hotels near La Recova Artisan Walk
- Hotels near Catedral de Santa Cruz
- Hotels near Ethno-folkloric Museum
- Hotels near Artecampo
- Hotels near Municipal Botanical Garden of Santa Cruz
- Hotels near Guarani Nandereko Nomai Art and Culture Center
- Hotels near Sacred Art Museum
- Hotels near Municipal Library
- Hotels near Arenal Park
- Hotels near Franco Aleman Cultural Center
- Hotels with Parking in Santa Cruz
- Hotels with Free Breakfast in Santa Cruz
- Hotels with a Pool in Santa Cruz
- Business Hotels in Santa Cruz
- Family Hotels in Santa Cruz
- Hotels with a Gym in Santa Cruz
- Resorts and Hotels with Spas in Santa Cruz
- Pet-Friendly Hotels in Santa Cruz
- Cheap Hotels in Santa Cruz
- Hotels with Kitchens in Santa Cruz
- Luxury Hotels in Santa Cruz
- Premium Suites Deluxe Aparthotel Equipetrol
- Hotel Continental Park
- Equipetrol Suites Apart Hotel
- Buganvillas Hotel Suites & Spa
- Alfonsina Hotel Boutique by Inboccaluppo
- Hotel BY Armonia SCZ
- Casa Por Temporadas
- Hotel G
- Cosmopolitano Hotel Boutique
- Swissôtel Santa Cruz De La Sierra
- Hotel Arenal
- Terranova Suites
- HOTEL OSHO
- Yotau All Suites Hotel
- Casa Vida
- Radisson Hotel Santa Cruz
- Prince Hotel
- Camino Real
- Apart Hotel Toborochi
- Hotel Viru Viru II
- Santos Apartamentos
- Buena Vista Rental House
- Hotel Canciller
- Senses Centro
- Hotel Las Palmas
- Hotel Misional
- Santa Cruz Departamentos
Most popular destinations
Hotels
- Perre La Mer Hotel Resort & Spa
- Prainha Village
- Hotels in Tobago
- Hotel Eliseo
- Hotel Mary
- Cyprotel Faliraki - All Inclusive
- Hotels in Ho Chi Minh City
- Lindner Hotel Frankfurt Hochst, part of JdV by Hyatt
- Hotel Artemis
- Hotels in Tampa
- Hotels with Kitchens in Paris
- Flamboyan Caribe Hotel & Spa
- Sia Split Hotel
- Hotel Iriarte Jauregia
- Cheap Hotels in Vienna
- Hotels near Allen Avenue
- 1908 Lisboa Hotel
- Hotels near Louvre Museum
- Hotels near Michigan Avenue
- Daima Biz Hotel - Dolusu Aquapark Access
- Park Regency Sharm El Sheikh Resort
- Hotels in Sharjah
- Akra Suites & Spa
- Andreolas Beach Hotel
- Connemara Coast Hotel
- Leonardo Hotel Eindhoven City Center
- Santa Monica Proper Hotel, a Member of Design Hotels
- Hotels in Bangkok Riverside
- 5 Star Hotels in Hurghada
- Hotels with a Gym in Lloret de Mar