Nestled in the heart of St. Louis, 21C Museum Hotel St Louis offers a luxurious retreat with an indoor pool, coffee shop/cafe, and gym. Indulge in a massage at the spa or enjoy billiards at the bar while relishing cooked-to-order breakfast options.
Reviews
9.09.0 out of 10
Wonderful
Popular amenities
Bar
Gym
24/7 front desk
Main amenities (12)
Daily housekeeping
Restaurants and bar/lounge
Indoor pool
Breakfast available
Fitness centre
Steam room
Valet parking
Room service
Coffee shop/cafe
Spa services
Business centre
Meeting rooms
Feel at home (6)
Premium TV channels
Daily housekeeping
Espresso maker
Blackout curtains
Pets allowed
Lift
The current price is €189
€189
includes taxes & fees
9 Mar - 10 Mar
Room options
Available filters for rooms
Showing 9 of 9 rooms
Loft, 2 Queen Beds
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Hairdryer
Bathrobes
Sleeps 4
2 Queen Beds
View all photos for Deluxe Room, 1 King Bed
Deluxe Room, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Hairdryer
Bathrobes
29 sq m
Sleeps 2
1 King Bed
View all photos for Room (Bunk Bed)
Room (Bunk Bed)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Private bathroom
Hairdryer
Sleeps 2
1 Single Bunk Bed
View all photos for Deluxe Double Room, 2 Queen Beds
Deluxe Double Room, 2 Queen Beds
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Shower/bath combination
Private bathroom
34 sq m
Sleeps 4
2 Queen Beds
Deluxe Room, Accessible (Accessible)
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Hairdryer
Bathrobes
Sleeps 2
1 King Bed
View all photos for Room, 1 King Bed, Corner
Room, 1 King Bed, Corner
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Hairdryer
Bathrobes
30 sq m
City view
Sleeps 2
1 King Bed
View all photos for Suite, 1 King Bed
Suite, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Hairdryer
Bathrobes
Sleeps 2
1 King Bed
View all photos for Deluxe Suite, 1 King Bed
Deluxe Suite, 1 King Bed
Highlights
Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Private bathroom
Hairdryer
Bathrobes
Sleeps 2
1 King Bed
View all photos for Luxury Double Room, 2 Queen Beds
Lambert-St. Louis International Airport (STL) - 26 min drive
St. Louis, MO (SUS-Spirit of St. Louis) - 32 min drive
St. Louis Gateway Station - 14 min walk
Kirkwood Station - 24 min drive
8th and Pine Station - 13 min walk
Convention Center Station - 16 min walk
Stadium Station - 19 min walk
Restaurants
Rosalita's Cantina - 6 min walk
Grand Hall Lounge Union Station - 11 min walk
Hair of the Dog - 7 min walk
Peabody Lounge - 6 min walk
Medina Mediterranean Grill - 5 min walk
About this property
21C Museum Hotel St Louis
21C Museum Hotel St Louis puts you in a great location, within a short 10-minute walk of City Museum and Enterprise Center. Guests indulge in massages, then grab a bite to eat at the coffee shop/cafe. Other features of this luxurious hotel include an indoor pool, a bar/lounge and a fitness centre. Fellow travellers say great things about the pool and helpful staff. Public transportation is close by: 8th and Pine Station is only 13 minutes on foot.
Languages
English
At a glance
Hotel size
104 rooms
Arriving/Leaving
Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age – 21
Check-out time is 11:00 AM
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Required at check-in
Credit card, debit card or cash deposit required for incidental charges
Government-issued photo ID may be required
Minimum check-in age is 21
Children
No cots (infant beds)
Pets
Pets allowed (dogs only)*
Service animals welcome
Internet
Free WiFi in public areas
Free WiFi in rooms
Parking
On-site valet parking (USD 45 per day; includes in/out privileges)
Other information
Smoke-free property
Property amenities
Food and drink
Cooked-to-order breakfast (surcharge) each morning 6:30 AM–1:00 PM
Guests can pamper themselves by indulging in the on-site spa services. Services include massages.
Fees & policies
Mandatory fees
You'll be asked to pay the following charges by the property at check-in or checkout. Fees may include applicable taxes:
Service fee: USD 5 per accommodation, per stay
Optional extras
Cooked-to-order breakfast is offered for an extra charge of approximately USD 10 to 25 per person
Pets
Service animals exempt from fees
Pets are allowed for an extra charge of USD 100 per accommodation, per stay
Parking
Valet parking costs USD 45 per day with in/out privileges
Pool, spa, & gym (if applicable)
Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation
Policies
This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Guests can rest easy knowing that there's a smoke detector and outdoor lighting on-site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
This property accepts credit cards. Cash is not accepted.
Credit cards accepted: Visa, Mastercard, American Express
Property Registration Number 832174967
Also known as
21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)
Frequently asked questions
Does 21C Museum Hotel St Louis offer free cancellation for a full refund?
Yes, 21C Museum Hotel St Louis does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in, depending on the property's cancellation policy. Just make sure that you check this property's cancellation policy for the exact terms and conditions.
Is there a pool at 21C Museum Hotel St Louis ?
Yes, there's an indoor pool.
Are pets allowed at 21C Museum Hotel St Louis ?
Yes, dogs are welcome. There's a charge of USD 100 per accommodation, per stay. Service animals are exempt from fees.
Is parking offered on site at 21C Museum Hotel St Louis ?
Yes. Valet parking costs USD 45 per day.
What are the check-in and check-out times at 21C Museum Hotel St Louis ?
Check-in start time: 4:00 PM; check-in end time: 11:00 AM. Check-out time is 11:00 AM.
Is there an on-site casino at 21C Museum Hotel St Louis ?
No, this hotel doesn't have a casino, but Horseshoe St. Louis Casino (3-min drive) and Casino Queen (4-min drive) are both nearby.
What is there to do at 21C Museum Hotel St Louis and nearby?
21C Museum Hotel St Louis has an indoor pool and a steam room, as well as spa services.
Are there restaurants at or near 21C Museum Hotel St Louis ?
Yes, there's an on-site restaurant.
What's the area around 21C Museum Hotel St Louis like?
21C Museum Hotel St Louis is in Downtown West, a short 6-minute walk from City Museum and 12 minutes' walk from St. Louis Union Station. Travellers love the hotel's prime location.
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21C Museum Hotel St Louis Reviews
Reviews
9.0
Wonderful
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.4/10
Cleanliness
9.2/10
Staff & service
9.2/10
Amenities
9.4/10
Property conditions & facilities
9.2/10
Eco-friendliness
Reviews
10/10 Exceptional
2 March 2025
Great bed, pillows and linens!
Trista
Trista, 1-night trip
10/10 Exceptional
23 February 2025
The space was beautiful, the food was delicious, and the staff was welcoming and kind.
Verified traveller
2-night trip
10/10 Exceptional
27 February 2025
Great for a Blues Game!
Super unique and fun hotel :)
Jennifer
Jennifer, 1-night trip
10/10 Exceptional
1 January 2025
Great stay
Fabulous hotel, decor amazing, loved the museum, room was perfect
Denise
Denise, 1-night trip
10/10 Exceptional
16 February 2025
Very good
Great hotel, great restaurant and bar, rooms were nice and they lots of activities you can do if you have some downtime
Oivin
Oivin, 3-night trip
10/10 Exceptional
25 January 2025
Convenient & Clean
Beautiful hotel with a perfect location! Staff was very friendly and vallet was so fast!
Bailey
Bailey, 1-night trip
10/10 Exceptional
20 February 2025
Five Stars
The staff provided exceptional service. I was highly satisfied with the accommodations; the online photos do not fully capture the hotel's beauty. The hotel was impeccably clean. I thoroughly enjoyed my stay and plan to return.
PRINCE
PRINCE, 1-night trip
10/10 Exceptional
25 February 2025
21C Top of The Arch
Love the Penguins and the Vibe
michael
michael, 2-night trip
10/10 Exceptional
3 March 2025
The staff were incredibly helpful and very friendly. The room was clean, the valet was super convenient, and the food was delightful. We loved the pool and the art museum. The only complaint was our shower door wouldn't fully close. It was a minor inconvenience that did not greatly impact our stay.
Jessica
Jessica, 1-night trip
8/10 Very good
4 March 2025
My 5 day stay in STL
This was my first time in STL. I enjoyed my stay. The room was clean. The service was nice. I really enjoyed the hotel amenities such as the pool and gym. I went to the gym almost every day. I also like the location because it was walking distance to the arch and other downtown attractions.
Curtis
Curtis, 4-night trip
10/10 Exceptional
19 November 2024
Our stay was amazing. My wife and I stayed for our anniversary and we enjoyed our stay here.
Brent
Brent, 1-night trip
10/10 Exceptional
5 November 2024
Beautiful hotel !
Stenisha
Stenisha, 1-night trip
10/10 Exceptional
12 February 2025
Thoroughly impressed
21C is a class act. It’s everything you didn’t realize you need in an accommodation. The ambiance is unmatched.
Alvin
Alvin, 1-night trip
10/10 Exceptional
5 December 2024
Good Stay
One of our favorite hotels in STL. Nice hotel in a good location and reasonably priced.
Verified traveller
1-night trip
10/10 Exceptional
12 January 2025
Great stay in unique hotel
I had a great stay. The property was very unique. I loved the museum and decor. The restaurant and bar had great food. I also enjoyed the fitness and pool areas. If I’m in the city I would stay again.
Patrice
Patrice, 2-night trip
6/10 Good
2 March 2025
Great accept on the orange pillow on my bed with white stains...what the heck was that?
Other than that great
David
David, 3-night trip
10/10 Exceptional
16 December 2024
We had a wonderful stay! Beautuful hotel. Great bar. Great food. Amazing service!
Denise
Denise, 2-night trip
10/10 Exceptional
13 December 2024
Amazing space. Friendly staff, location convenient. Absolutely will stay again when I'm back in town.
Erin
Erin, 2-night trip
10/10 Exceptional
25 November 2024
Great hotel! Fully recommend!
Amazing place! It is like lodging in a museum. Also the restaurant is amazing!
Carolina
Carolina, 1-night trip
10/10 Exceptional
18 January 2025
Stay here instead of a conference hotel!
Lovely two-night stay at the 21c STL. Very reasonable room price, nice bar and very good restaurant, comfy "gameroom" for hanging out. Thoughtful art and interior design as you would expect from a 21c property. Yummy coffee/tea/breakfast shop.
Verified traveller
2-night trip
10/10 Exceptional
15 October 2024
Very nice and comfortable stay
Annie
Annie, 1-night trip
10/10 Exceptional
16 November 2024
Perfect stay
We loved this hotel—beautiful rooms, comfortable beds, fantastic gym, delicious food and cocktails and friendly staff!
Verified traveller
1-night trip
10/10 Exceptional
4 December 2024
Great one night stay wish I could have enjoyed the pool
Takia
Takia, 1-night trip
10/10 Exceptional
9 November 2024
The front desk staff was amazing!
Mendy
Mendy, 1-night trip
10/10 Exceptional
4 January 2025
Highly recommend!
Beautiful property! Loved the decor. The rooms we chose was large (2 beds) and comfortable. Very clean and modern. Great bar! Mason is a great bartender!