Hotels in Mytilene

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Check prices for these dates

Tonight
31 May - 1 Jun
Tomorrow
1 Jun - 2 Jun
Next weekend
6 Jun - 8 Jun
In two weeks
13 Jun - 15 Jun

Where to stay in Mytilene?

ISSA Lesvos
Front of property

ISSA Lesvos

10.0 out of 10, Exceptional, (2)
The price is €113
includes taxes & fees
1 Jun - 2 Jun
ISSA Lesvos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mytilene

Port of Mytilene

Explore the waterfront in Mytilene with a trip to Port of Mytilene. While you're in the area, stroll along the seaside.

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Port of Mytilene

Learn more about Mytilene

Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

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Frequently asked questions

Can I book a refundable accommodation option in Mytilene?
If you want the flexibility to change your plans to Mytilene, most hotels offer refundable* rates that you can book. You can find this accommodation by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Mytilene if I want a holiday rental instead of a hotel?
You’ll find 14 holiday homes on our site. You can also book one of 24 apartments or 18 villas.
What will the weather in Mytilene be like during my visit?
The warmest months in Mytilene are usually August and July, with an average temperature of 25°C. January and February are the chilliest months, when the average temperature is 11°C. The rainiest months are January and December.
Why should I book my Mytilene hotel with Hotels.com?
There are plenty of reasons to book your Mytilene travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.