Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on comfort, location and traveller experience. Last updated on .
Hotels in Cape Girardeau
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10 Aug - 11 AugTomorrow
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14 Aug - 16 AugNext weekend
21 Aug - 23 AugWhere to stay in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
€98
includes taxes & fees
16 Aug - 17 Aug
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
€70
includes taxes & fees
16 Aug - 17 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
€83
includes taxes & fees
19 Aug - 20 Aug
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
€88
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
€107
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
€103
includes taxes & fees
20 Aug - 21 Aug
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
€123
includes taxes & fees
21 Aug - 22 Aug
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
€88
includes taxes & fees
23 Aug - 24 Aug
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
€85
includes taxes & fees
16 Aug - 17 Aug
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
€60
includes taxes & fees
6 Sept - 7 Sept
Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
€71
includes taxes & fees
16 Aug - 17 Aug
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
€74
includes taxes & fees
16 Aug - 17 Aug
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
€87
includes taxes & fees
12 Aug - 13 Aug
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
€79
includes taxes & fees
7 Sept - 8 Sept
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
€79
includes taxes & fees
12 Aug - 13 Aug
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Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
€107
for 1 room
includes taxes & fees
€88
for 1 room
includes taxes & fees
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
€127
for 1 room
includes taxes & fees
€112
for 1 room
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
€126
for 1 room
includes taxes & fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
€111
for 1 room
includes taxes & fees
€131
for 1 room
includes taxes & fees
€112
for 1 room
includes taxes & fees
€111
for 1 room
includes taxes & fees
€73
for 1 room
includes taxes & fees
€96
for 1 room
includes taxes & fees
Check out hotels with a pool in Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
€107
includes taxes & fees
16 Aug - 17 Aug
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
€98
includes taxes & fees
16 Aug - 17 Aug
€88
includes taxes & fees
16 Aug - 17 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
€83
includes taxes & fees
19 Aug - 20 Aug
€103
includes taxes & fees
20 Aug - 21 Aug
€88
includes taxes & fees
23 Aug - 24 Aug
€85
includes taxes & fees
16 Aug - 17 Aug
€60
includes taxes & fees
6 Sept - 7 Sept
You may also like pet-friendly hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
€98
includes taxes & fees
16 Aug - 17 Aug
€88
includes taxes & fees
16 Aug - 17 Aug
€103
includes taxes & fees
20 Aug - 21 Aug
€70
includes taxes & fees
16 Aug - 17 Aug
€88
includes taxes & fees
23 Aug - 24 Aug
€71
includes taxes & fees
16 Aug - 17 Aug
€85
includes taxes & fees
16 Aug - 17 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Cape Girardeau
Pet friendly
Family friendly
Our prices for hotels in Cape Girardeau are cheapest in December
Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveller single night rates
Top landmarks in Cape Girardeau
Southeast Missouri State University
8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
Riverfront Bridge Park
8.8/10 (129 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Century Casino & Hotel Cape Girardeau is 0.5 mi (0.8 km) from central Cape Girardeau, why not stop by during your stay?
Riverfront Park
8.0/10 (2 reviews)
Riverfront Park is worth a visit when in central Cape Girardeau.
Cape Splash Family Aquatic Center
8.6/10 (21 reviews)
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau? If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center, located nearby.
Hunter Valley Winery
7.4/10 (48 reviews)
Travellers might want a tour of Hunter Valley Winery, just one of the places to visit, located 9.3 mi (14.9 km) from central Cape Girardeau.
Cape Rock Park
8.6/10 (36 reviews)
Cape Rock Park is worth a visit, located 1.9 mi (3.1 km) from central Cape Girardeau.
Show Me Center
8.6/10 (40 reviews)
You can catch an event at Show Me Center, located 1.1 mi (1.8 km) from central Cape Girardeau.
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.
See all hotels in Cape Girardeau
Check out reviews of Cape Girardeau hotels guests love
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Our stove had a short in it so I wasn’t able to cook"
Tru By Hilton Cape Girardeau
10/10 Excellent
"Breakfast menu was limited but ok for most people. The room was very comfortable, cozy and clean."
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"Everything about this property is 1000000/100000"
Town House Inn Cape Giradreau
10/10 Excellent
"Good atat"
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"Very nice hotel and staff. Would definitely recommend "
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"the staff was very understanding and helpful"
Drury Inn & Suites Cape Girardeau
10/10 Excellent
"Everything was awesome, highly recommended this hotel"
Hampton Inn Cape Girardeau I 55 East
10/10 Excellent
"Good Job!"
Fairfield Inn & Suites by Marriott Cape Girardeau
10/10 Excellent
"I had a great stay! Everything looked new and well maintained. The room was very clean, comfortable, and inviting. The hotel's location was perfect—it was close to everything I needed, which made getting around easy. I would definitely stay here again and recommend it to anyone visiting the area."
Frequently asked questions
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