Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on comfort, location and traveller experience. Last updated on .
Hotels in Cape Girardeau
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Cape Girardeau?

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (141 reviews)
The price is €89
includes taxes & fees
5 Jul - 6 Jul

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (203 reviews)
The price is €92
includes taxes & fees
9 Jul - 10 Jul

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (612 reviews)
The price is €131
includes taxes & fees
29 Jun - 30 Jun

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
The price is €99
includes taxes & fees
5 Jul - 6 Jul

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
The price is €95
includes taxes & fees
12 Jul - 13 Jul

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
The price is €71
includes taxes & fees
12 Jul - 13 Jul

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is €109
includes taxes & fees
27 Jul - 28 Jul

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (826 reviews)
The price is €105
includes taxes & fees
12 Jul - 13 Jul

Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.0 out of 10, Good, (768 reviews)
The price is €67
includes taxes & fees
5 Jul - 6 Jul

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (525 reviews)
The price is €125
includes taxes & fees
12 Jul - 13 Jul

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.0 out of 10, Very good, (969 reviews)
The price is €89
includes taxes & fees
5 Jul - 6 Jul

Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
6.2 out of 10, (230 reviews)
The price is €77
includes taxes & fees
10 Jul - 11 Jul

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
The price is €76
includes taxes & fees
26 Jul - 27 Jul

EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.6 out of 10, Exceptional, (101 reviews)
The price is €98
includes taxes & fees
29 Jun - 30 Jun

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (789 reviews)
The price is €88
includes taxes & fees
30 Jun - 1 Jul

Hotel 7 Inn Anna
Hotel 7 Inn AnnaAnna
6.6 out of 10, (230 reviews)
The price is €81
includes taxes & fees
29 Jun - 30 Jun

Makanda Inn
Makanda InnMakanda
10.0 out of 10, Exceptional, (37 reviews)
The price is €262
includes taxes & fees
29 Jun - 30 Jun

Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.2 out of 10, Very good, (771 reviews)
The price is €89
includes taxes & fees
30 Jun - 1 Jul

Town House Inn
Town House InnJackson
7.6 out of 10, Good, (446 reviews)
The price is €75
includes taxes & fees
29 Jun - 30 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out hotels with a pool in Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1002)
The price is €109
includes taxes & fees
27 Jul - 28 Jul
You may also like pet-friendly hotels in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1006)
The price is €99
includes taxes & fees
5 Jul - 6 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Cape Girardeau
Pet friendly
Top landmarks in Cape Girardeau
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

Check out reviews of Cape Girardeau hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center
8/10 Good
Frequently asked questions
Keep exploring
- Delta Hotels
- Chaffee Hotels
- Miner Hotels
- Bell City Hotels
- Hotels near Marston Community Center
- Malden Hotels
- Friedheim Hotels
- Ste Genevieve Hotels
- Dexter Hotels
- Hotels near Lazy L Safari Park
- Hotels near Lake Wappapello
- Perryville Hotels
- Hotels near Hunter Valley Winery
- Hotels with a Pool in Cape Girardeau
- Dudley Hotels
- Hotels near City of Miner Convention Center
- Hotels near Sainte Genevieve Winery
- Marston Hotels
- Fruitland Hotels
- Hotels near eDen Spa & Salon



































































