Hotels in Cape Girardeau

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Tonight
2 Nov - 3 Nov
Tomorrow
3 Nov - 4 Nov
This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Where to stay in Cape Girardeau?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on quality, location and traveller experience. Last updated on 2 November 2026.
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

1. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (699 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is €116
includes taxes & fees
3 Nov - 4 Nov
The Riverview
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Centre.
The price is €101
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with marble flooring, elegant seating, and a grand staircase.

3. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (556 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this city centre Marriott. The Bistro serves American cuisine while in-room refrigerators and washing machines/dryers enhance comfort. Enjoy the 24-hour fitness centre after visiting nearby Riverfront Park and Isle Casino.
The price is €118
includes taxes & fees
15 Nov - 16 Nov
Courtyard by Marriott Cape Girardeau Downtown
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

4. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Centre with free WiFi and parking.
The price is €91
includes taxes & fees
8 Nov - 9 Nov
Drury Inn & Suites Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

5. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (856 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness centre, or relax on the terrace after exploring nearby aquatic attractions.
The price is €99
includes taxes & fees
8 Nov - 9 Nov
Hampton Inn Cape Girardeau I 55 East
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

6. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness centre, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is €101
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

7. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,003 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Centre and Conservation Nature Centre. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is €73
includes taxes & fees
8 Nov - 9 Nov
Pear Tree Inn Cape Girardeau West
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (239 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Centre.
The price is €102
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

9. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very good, (1,000 reviews)
The price is €77
includes taxes & fees
22 Nov - 23 Nov
Candlewood Suites Cape Girardeau by IHG
A modern retail area with a display of local items and snacks.

10. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (199 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness centre.
The price is €91
includes taxes & fees
9 Nov - 10 Nov
Tru By Hilton Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.0 out of 10, Good, (816 reviews)
Escape to this welcoming hotel featuring an outdoor pool and free daily English breakfast. Just minutes from Mississippi River and popular attractions, with free WiFi and parking. Guests rave about the helpful staff ready to make your stay enjoyable.
The price is €60
includes taxes & fees
8 Nov - 9 Nov
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.2 out of 10, Good, (243 reviews)
Wake up to adventure at this Cape Girardeau motel near the Family Aquatic Centre and Show Me Centre. Enjoy hassle-free travel with free WiFi, complimentary parking, and 24-hour front desk service for your Missouri getaway.
The price is €73
includes taxes & fees
3 Nov - 4 Nov
Town House Inn Cape Giradreau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (890 reviews)
The price is €77
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

14. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.0 out of 10, Very good, (785 reviews)
Begin your day with a complimentary breakfast at this Jackson hotel near Mississippi River and Shawnee National Forest. The indoor pool offers year-round swimming while free WiFi and parking add value. Cape Girardeau Conservation Nature Centre awaits nearby.
The price is €73
includes taxes & fees
22 Nov - 23 Nov
Comfort Suites Jackson-Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

15. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,001 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is €76
includes taxes & fees
8 Nov - 9 Nov
Drury Inn & Suites Jackson MO
A living room with a blue wall, a fireplace, a sofa, and a chair.

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
Adventure seekers can explore nearby hiking trails, kayaking, and rafting, then return to this welcoming hotel. Enjoy free continental breakfast, WiFi, and parking, plus exceptional service from the staff that guests consistently praise.
The price is €103
includes taxes & fees
3 Nov - 4 Nov
EC Reed's Mercantile and Hotel
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

17. Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (450 reviews)
Feel welcomed at this cosy motel with friendly service just minutes from Shawnee National Forest. Enjoy convenient perks including complimentary WiFi and parking, plus easy access to Litz Park and Lazy L Safari Park for outdoor adventures.
The price is €77
includes taxes & fees
3 Nov - 4 Nov
Town House Inn
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

18. Makanda Inn

Makanda Inn
3.5 star property
Makanda
10.0 out of 10, Exceptional, (41 reviews)
Tucked near a train station in Makanda, this B&B offers a tranquil escape with massage services and a welcoming bar. Explore nearby Makanda Boardwalk after breakfast, then unwind on the terrace as forest sounds serenade your evening.
The price is €268
includes taxes & fees
3 Nov - 4 Nov
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out pet-friendly hotels in Cape Girardeau

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1003)
The price is €73
includes taxes & fees
8 Nov - 9 Nov
Pear Tree Inn Cape Girardeau West
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You can also stay at hotels with a pool in Cape Girardeau

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1007)
The price is €101
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Cape Girardeau

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When is the best time to visit Cape Girardeau?

Our prices for hotels in Cape Girardeau are cheapest in December

Price trends for hotels in Cape Girardeau

Pricing is based on two traveller single night rates
View properties in November
Currently viewing crowd sizes and weather for November.

November

High 13°C / low 4°C. Partly sunny.
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November, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Sunny most days.
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April, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in Cape Girardeau

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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Learn more about Cape Girardeau

Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

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A nighttime view of a bridge with its cables illuminated against a starry sky.

Frequently Asked Questions

Can I book a refundable accommodation option in Cape Girardeau?

If you want the flexibility to change your plans to Cape Girardeau, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Cape Girardeau if I want a holiday rental instead of a hotel?

If you want to find a good alternative to a hotel, review our selection of 30 holiday homes. In addition, you can choose from 20 apartments.

What will the weather in Cape Girardeau be like during my visit?

July and August are typically the warmest months in Cape Girardeau, when the average temperature is 25°C. January and February are the coldest months, when the average temperature is 5°C. April and March are the months with the most rain.

Why should I book my Cape Girardeau hotel with Hotels.com?

There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

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