If you're looking for a place to get away, look no further than Santa Isabel. Whether you're planning to stay for a night or for the week, the area around Santa Isabel has accommodation options to fit every need. Search for hotels in Santa Isabel with Hotels.com by checking our online map. Our map displays the areas and neighbourhoods around all Santa Isabel hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santa Isabel hotel deals are here with our lowest price guarantee.
Hotels in Santa Isabel
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Santa Isabel?

Cabins on paradise San Blas island
Cabins on paradise San Blas island
The price is €293
includes taxes & fees
11 May - 12 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Santa Isabel
While in the area, you can enjoy nearby attractions like Porvenir Museum.
Frequently asked questions
Find out more about Santa Isabel
Find out more about Santa Isabel
Keep exploring
Keep exploring
- Panama City Hotels
- Bocas del Toro Hotels
- Rio Hato Hotels
- Bastimentos Hotels
- Boquete Hotels
- Veracruz Hotels
- Colon Hotels
- El Valle de Anton Hotels
- Tocumen Hotels
- San Blas Islands Hotels
- David Hotels
- Isla Frangipani Hotels
- Playa Coronado Hotels
- Santa Catalina Hotels
- San Carlos Hotels
- Nueva Gorgona Hotels
- Boca Chica Hotels
- Punta Chame Hotels
- Ancon Hotels
- El Chiru Hotels
Most popular destinations
Hotels
Rosedale On Robson Suite HotelHotels near Hampton Court PalaceHotel AlisiosHotel Boutique La Marquesina - Adults OnlySpark by Hilton LutonA.P. Acropolis View ApartmentsBallygally Seaview and Garden 1 Bedroom HideawayCheap Hotels in HalifaxApartamentos Panorama Only AdultsAppart Hotel Odalys City Centre Compans CaffarelliVIP Executive Eden AparthotelMelia LebrerosHotels in Panama CityFairways Hotel DundalkHotels in Bocas del ToroHotels in Old Town BenidormHilton Garden Inn Brussels City CentreAddress DowntownMonte dos Avós Apartamentos, AlbufeiraFamily Hotels in AntibesHotels near Tallinn Christmas MarketsFamily Hotels in MannheimThe Stone House B&BBest Western Plus Hollywood/AventuraEight Hotel PortofinoFerienhotel FuchsHotels in DavidCoral Sea ResortBeach Hotels in DohaHotels near Andheri Sports Complex