Your safety is our top priority
Hotels in Cayo Guillermo
Why book with Hotels.com?
Where to stay in Cayo Guillermo?
- Club Cayo Guillermo - All Inclusive
Club Cayo Guillermo - All Inclusive3.5-star
2.3 miles to city centreGuest rating6.0.Good1 Hotels.com guest review
- Sol Cayo Guillermo - All Inclusive
Sol Cayo Guillermo - All Inclusive3.5-star
1.4 miles to city centreGuest rating4.6.Fair12 Hotels.com guest reviews
- Iberostar Daiquirí
1.9 miles to city centreGuest rating6.4.Good37 Hotels.com guest reviews
- Villa Gregorio
1.3 miles to city centreGuest rating7.6.Good9 Hotels.com guest reviews
- Hotel Grand Muthu Cayo Guillermo
Hotel Grand Muthu Cayo Guillermo3.5-star
1 mile to city centre
- Aparthotel Azul
19.5 miles to city centreGuest rating4.0.Fair1 Hotels.com guest review
- Melia Cayo Guillermo - All Inclusive
Melia Cayo Guillermo - All Inclusive4-star
16.1 miles to city centreGuest rating6.4.Good46 Hotels.com guest reviews
- Aparthotel Azul
19.6 miles to city centre
- Sitio La Guira
Sitio La Guira2.5-star
18 miles to city centreGuest rating10.0.Exceptional1 Hotels.com guest review
- Villa Gaviota Cayo Coco
Villa Gaviota Cayo Coco
24.3 miles to city centre
- Grand Memories Santa Maria - All Inclusive
Grand Memories Santa Maria - All Inclusive3.5-star
23.1 miles to city centreGuest rating5.6.Fair62 Hotels.com guest reviews
- Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive
Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive3.5-star
23 miles to city centreGuest rating6.4.Good31 Hotels.com guest reviews
Find out more about Cayo Guillermo
Our 3 most booked Cayo Guillermo hotels from the last hour are:
1. Villa Gregorio
2. Iberostar Daiquirí
3. Club Cayo Guillermo - All Inclusive
But low prices and a great selection are not the only thing Hotels.com offers. We also have numerous guest reviews for Cayo Guillermo, so you can get a better idea of where you're staying and what you should expect.
Why use Hotels.com to book your Cayo Guillermo accommodation?
We can help you to find the perfect Cayo Guillermo hotel room for almost any occasion. With our fast and secure hotel search you can easily compare different Cayo Guillermo hotels by:
- - Price
- - Availability
- - Cayo Guillermo neighbourhoods
- - Nearby Cayo Guillermo attractions and landmarks
- - Genuine Hotels.com guest reviews for Cayo Guillermo
- - Star rating
- - Amenities
- - Hotel name & chain
- - Theme
Alternatively, you can use our detailed Cayo Guillermo maps showing hotel locations in Cayo Guillermo, using all the filters listed above.
Cheap Cayo Guillermo hotels - getting the best deal
On Hotels.com you can always be sure you're getting the best deal.
We make it easy to save money on every booking. We offer our Price Guarantee on most bookings. Plus we offer 2 more ways to save:
1. Hotels.com Rewards - Collect 10 nights, get 1 free*
2. Hotels.com Deals & Discounts - Search over 10,000 deals!
Not sure where to go? Here are some popular destinations you may like
- Cayo Coco
- Santa Clara
- Cayo Santa Maria
Not found the right property yet? Explore other destinations or refine your current search further.