Hotels & Accommodation in Cayo Guillermo

Search Cayo Guillermo Hotels

Hotels.com™ Rewards

Collect 10 nights, get 1 reward night

And look out for Secret Prices on selected hotels

  • Pay now or later on most rooms
  • Free cancellation on most rooms
  • Price Guarantee

Best Cayo Guillermo Hotels

Hotels.com currently has plenty of hotels in Cayo Guillermo that you can book from the comfort of your home!

Our 3 most booked Cayo Guillermo hotels from the last hour are:

1. Sercotel Club Cayo Guillermo Hotel - All Inclusive
2. Sol Cayo Guillermo
3. IBEROSTAR Daiquirí - All Inclusive


But low prices and a great selection are not the only thing Hotels.com offers. We also have numerous guest reviews for Cayo Guillermo, so you can get a better idea of where you're staying and what you should expect.

Why use Hotels.com to book your Cayo Guillermo accommodation?

We can help you to find the perfect Cayo Guillermo hotel room for almost any occasion. With our fast and secure hotel search you can easily compare different Cayo Guillermo hotels by:

  • - Price
  • - Availability
  • - Cayo Guillermo neighbourhoods
  • - Nearby Cayo Guillermo attractions and landmarks
  • - Genuine Hotels.com guest reviews for Cayo Guillermo
  • - Star rating
  • - Amenities
  • - Hotel name & chain
  • - Theme


Alternatively, you can use our detailed Cayo Guillermo maps showing hotel locations in Cayo Guillermo, using all the filters listed above.

Cheap Cayo Guillermo hotels - getting the best deal

On Hotels.com you can always be sure you're getting the best deal.

We make it easy to save money on every booking. We offer our Price Guarantee on most bookings. Plus we offer 2 more ways to save:

1. Hotels.com Rewards - Collect 10 nights, get 1 free*
2. Hotels.com Deals & Discounts - Search over 10,000 deals!